121679-24-1 Usage
General Description
(E)-N-Methyl-2-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]ethenesulfonamide, also known as E-4031, is a chemical compound with potential pharmaceutical applications. It belongs to the class of sulfonamides and is often used as a potassium channel blocker, particularly in research related to cardiac arrhythmias and disorders. (E)-N-Methyl-2-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]ethenesulfonamide exhibits its pharmacological activity by inhibiting the rapidly activating delayed rectifier potassium current (IKr) and prolonging the cardiac action potential duration. It has shown promise in the treatment of certain heart conditions and has been studied in preclinical and clinical trials for its antiarrhythmic properties. However, caution should be taken with the use of E-4031, as it may have potential side effects and contraindications.
Check Digit Verification of cas no
The CAS Registry Mumber 121679-24-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,6,7 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 121679-24:
(8*1)+(7*2)+(6*1)+(5*6)+(4*7)+(3*9)+(2*2)+(1*4)=121
121 % 10 = 1
So 121679-24-1 is a valid CAS Registry Number.
121679-24-1Relevant articles and documents
Indole derivatives
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, (2008/06/13)
Compounds are disclosed of formula (I) STR1 wherein R1 represents H or C1-6 alkyl; R2 represents H or C1-6 alkyl; R3 represents H; R4 represents H or C1-3 alkyl; and pharmaceutically acceptable salts and solvates (for example hydrates thereof. The compounds are indicated as useful for the treatment of migraine, cluster headache, chronic paroxysmal hemicrania and headache associated with vascular disorders. Processes and intermediates for their preparation and pharmaceutical compositions containing them are also disclosed.
