121700-07-0

Upstream product

• 14994-75-3 4-hydroxy-1-phenylquinolin-2(1H)-one 
• 106-96-7 propargyl bromide 

Downstream Products

• 439600-19-8 1-phenyl-4-prop-2-ynyloxy-1H-quinoline-2-thione 
• 121673-75-4 2-Methyl-5-phenyl-5H-furo[3,2-c]quinolin-4-one 

Relevant academic research and scientific papers

Regioselective synthesis of thieno[2,3-b]quinolin-4(9H)-ones: Occurrence of thermal [1,3] sigmatropic rearrangement

A number of hitherto unreported thieno[2,3-b]quinolin-4(9H)-ones 5a-f have been regioselectively synthesized from the corresponding 4-(prop-2-ynyloxy)quinolin-2(1H)-thiones 4a-f. The 4-(Prop-2-ynyloxy)quinolin-2(1H)-thiones 4a-f were prepared by the thionation of 4-(prop-2-ynyloxy)quinolin-2(1H)-ones 3a-f. The latter compounds were in turn prepared by the alkylation of 4-hydroxyquinolin-2(1H)-one (1).

An efficient route to diverse 2H-pyrano[3,2-c]quinolin-5(6H)-ones via electrophilic cyclization reactions

Electrophilic cyclization of 4-((3-arylprop-2-yn-1-yl)oxy)quinolin-2(1H)-one derivatives with iodine leads to the formation of 2H-pyrano[3,2-c]quinolin-5(6H)-ones bearing an alkenyl iodide moiety in good to excellent yields under mild conditions. The resu