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1217052-16-8

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1217052-16-8 Usage

Uses

Epinastine analogue.

Check Digit Verification of cas no

The CAS Registry Mumber 1217052-16-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,0,5 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1217052-16:
(9*1)+(8*2)+(7*1)+(6*7)+(5*0)+(4*5)+(3*2)+(2*1)+(1*6)=108
108 % 10 = 8
So 1217052-16-8 is a valid CAS Registry Number.

1217052-16-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-Bromo Epinastine

1.2 Other means of identification

Product number -
Other names 7-Bromoepinastine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1217052-16-8 SDS

1217052-16-8Downstream Products

1217052-16-8Relevant articles and documents

Synthetic method of epinastine hydrochloride impurity B

-

Paragraph 0033-0035, (2017/09/12)

The invention relates to the field of pharmaceutical technology and, and particularly relates to a preparation process of an epinastine hydrochloride impurity. The method comprises: firstly, using 6-(phthalimidomethyl)-6,11-dihydro-5H-dibenz[b,e]azepine (shown in the description) as a starting material, removing a protective group with hydrazine hydrate and then performing ring closure with cyanogen bromide to obtain 3- amino-9,13-dihydro-1H-dibenzo [c,f ]-imidazo [1,5-a] heterocyclic nitrogen (shown in the description) (epinastine), and finally reacting with a simple substance bromine to obtain the epinastine hydrochloride impurity B. The synthetic method of the epinastine hydrochloride impurity B has the advantages of being simple in process route, convenient to operate, good in selectivity and high in yield. The synthetic epinastine hydrochloride impurity B can be used as a control substance for testing a related substance of epinastine hydrochloride, can be applied in quality control of epinastine hydrochloride and related preparations thereof, and can be used for controlling the purity of the epinastine hydrochloride active pharmaceutical ingredients or preparations thereof.

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