1217109-99-3Relevant articles and documents
Ultrasound-assisted one-pot, three-component synthesis of spiro[indoline-3,4′-pyrazolo[3,4-b]pyridine]-2,6′(1′H)-diones in water
Bazgir, Ayoob,Ahadi, Somayeh,Ghahremanzadeh, Ramin,Khavasi, Hamid Reza,Mirzaei, Peiman
experimental part, p. 447 - 452 (2010/12/25)
A simple, facile, efficient and three-component procedure for the synthesis of spiro[indoline-3,4′-pyrazolo[3,4-b]pyridine]-2,6′(1′H)-diones by the reaction of 4-hydroxycumarin, isatins and 1H-pyrazol-5-amines in water under ultrasonic irradiation is reported. The advantages of this method are the use of an inexpensive and readily available catalyst, easy work-up, good yields, and the use of water as a solvent that is considered to be relatively environmentally benign.