121721-95-7

Basic information

• Product Name: C₁₅H₁₃FO
• Synonyms: C₁₅H₁₃FO
• CAS NO: 121721-95-7
• Molecular Weight: 228.266
• Mol File: 121721-95-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₃FO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₃FO(121721-95-7)
• EPA Substance Registry System: C₁₅H₁₃FO(121721-95-7)

Safety Data

• Hazardous Substances Data: 121721-95-7(Hazardous Substances Data)

Upstream product

• 324-94-7 4'-fluoro-biphenyl-4-ol 
• 106-95-6 allyl bromide 

Relevant articles and documents

Design, synthesis, and anti-proliferative evaluation of [1,1′-biphenyl]-4-ols as inhibitor of HUVEC migration and tube formation

Allylated biphenol neolignans contain a variety of chemopreventive entities that have been used as anti-tumor drug leads. Herein, 37 allylated biphenols were evaluated for anti-proliferative activity by the MTT assay and inhibitory effect on the migration and tube formation of HUVECs featuring anti-angiogenic properties. 3-(2-Methylbut-3-en-2-yl)-3′,5′-bis(trifluoromethyl)-[1, 1′-biphenyl]-4-ol (5c) exerted an inhibitory effect on HUVECs compared to honokiol (IC50 = 47.0 vs. 52.6 μM) and showed significant blocking effects on the proliferation of C26, Hela, K562, A549, and HepG2 (IC 50 = 15.0, 25.0, 21.2, 29.5, and 13.0 μM, respectively), superior to those of honokiol (IC50 = 65.1, 62.0, 42.0, 75.0, and 55.4 μM, respectively). Importantly, compound 5c inhibited the migration and capillary-like tube formation of HUVECs in vitro.