121723-80-6

Basic information

• Product Name: 7-Octen-4-one, 1-hydroxy-
• CAS NO: 121723-80-6
• Molecular Formula: C8H14O2
• Molecular Weight: 142.198
• Mol File: 121723-80-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-Octen-4-one, 1-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Octen-4-one, 1-hydroxy-(121723-80-6)
• EPA Substance Registry System: 7-Octen-4-one, 1-hydroxy-(121723-80-6)

Safety Data

• Hazardous Substances Data: 121723-80-6(Hazardous Substances Data)

Upstream product

• 920324-11-4 ethyl 3-oxo-2-[2-(tetrahydro-2H-pyran-2-yloxy)ethyl]hept-6-enoate 

Downstream Products

• 92362-24-8 trans-2-phenylselenomethyl-1,6-dioxaspiro<4.4>nonane 
• 92362-24-8 cis-2-phenylselenomethyl-1,6-dioxaspiro<4.4>nonane 
• 5451-15-0 cis-2-methyl-1,6-dioxaspiro<4.4>nonane 
• 5451-15-0 trans-2-methyl-1,6-dioxaspiro<4.4>nonane 
• 5451-15-0 (2S,5R)-2-methyl-1,6-dioxaspiro[4.4]nonane 
• 5451-15-0 (2R,5R)-2-methyl-1,6-dioxaspiro[4.4]nonane 
• 5451-15-0 (2S,5S)-2-methyl-1,6-dioxaspiro[4.4]nonane 
• 5451-15-0 (2R,5S)-2-methyl-1,6-dioxaspiro[4.4]nonane 
• 92362-19-1 2-(But-3-enyl)tetrahydrofuran-2-ol 

Relevant articles and documents

Organoselenium mediated asymmetric cyclizations. Synthesis of enantiomerically pure 1,6-dioxaspiro[4.4]nonanes

The asymmetric cyclization of 1-hydroxyoct-7-en-4-one, promoted by camphorselenenyl tetrafluoroborate, generated from camphor diselenide and silver tetrafluoroborate in dichloromethane at room temperature, afforded a mixture of two diastereoisomeric E- and two diastereoisomeric Z-2-[(camphorseleno)methyl]-1,6-dioxaspiro[4.4]nonanes. These were separated by medium pressure liquid chromatography and then deselenenylated with triphenyltin hydride and AIBN to give enantiomerically pure 2-methyl-1,6-dioxaspiro[4.4]nonanes. The camphorseleno group was also substituted by an allyl function using allyltributyltin in the presence of AIBN.