1217275-79-0

Basic information

• Product Name: (S)-1-benzyl-2-(((3-chloropropyl)dimethylsilyloxy)diphenylmethyl)pyrrolidine
• Synonyms: (S)-1-benzyl-2-(((3-chloropropyl)dimethylsilyloxy)diphenylmethyl)pyrrolidine
• CAS NO: 1217275-79-0
• Molecular Weight: 478.149
• Mol File: 1217275-79-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-benzyl-2-(((3-chloropropyl)dimethylsilyloxy)diphenylmethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-benzyl-2-(((3-chloropropyl)dimethylsilyloxy)diphenylmethyl)pyrrolidine(1217275-79-0)
• EPA Substance Registry System: (S)-1-benzyl-2-(((3-chloropropyl)dimethylsilyloxy)diphenylmethyl)pyrrolidine(1217275-79-0)

Safety Data

• Hazardous Substances Data: 1217275-79-0(Hazardous Substances Data)

Upstream product

• 10605-40-0 (3-chloropropyl)dimethylchlorosilane 
• 118970-95-9 (S)-1-benzyl-2-(hydroxydiphenylmethyl)pyrrolidine 

Downstream Products

• 1217275-80-3 (S)-1-(3-(((1-benzylpyrrolidin-2-yl)diphenylmethoxy)dimethylsilyl)propyl)-3-methyl-1H-imidazol-3-ium chloride 

Relevant articles and documents

Highly efficient ion-tagged catalyst for the enantioselective Michael addition of aldehydes to nitroalkenes

The ion-tagged diphenylprolinol silyl ether 6 very efficiently catalyzes the asymmetric Michael addition of aliphatic aldehydes to nitroalkenes with ee of up to > 99.5% at low catalyst loadings (0.25-5 mol%) and using only a slight excess of aldehydes (1.2-2 equiv.). This new organocatalyst can be used with the same outstanding efficiency in a wide variety of solvents and reaction coditions.