1217339-63-3Relevant academic research and scientific papers
Calixarene-derived chiral tertiary amine-thiourea organocatalyzed asymmetric Michael additions of acetyl acetone and dimethyl malonate to nitroolefins
Durmaz, Mustafa,Tataroglu, Aysun,Yilmaz, Horu,Sirit, Abdulkadir
, p. 148 - 156 (2016)
Novel bifunctional chiral thiourea-tertiary amines bearing a calix[4]arene scaffold were synthesized and applied in catalytic asymmetric Michael addition of acetyl acetone and dimethyl malonate to nitroolefins. The corresponding adducts were obtained in e
Impact of Tetracationic Calix[4]arene Conformation—from Conic Structure to Expanded Bolaform—on Their Antibacterial and Antimycobacterial Activities
Mourer, Maxime,Duval, Rapha?l E.,Constant, Patricia,Daffé, Mamadou,Regnouf-de-Vains, Jean-Bernard
, p. 911 - 921 (2019/03/13)
The four possible conformers of a new tetrakisguanidino calix[4]arene thought to interact deleteriously with bacterial membranes have been synthesized, characterized, and evaluated for their in vitro cytotoxicity and antibacterial activity against various
Synthesis and anticonvulsant evaluation of some N-substituted phthalimides
Wiecek, Malgorzata,Kiec-Kononowicz, Katarzyna
experimental part, p. 249 - 257 (2009/12/24)
Two series of phthalimides - one possessing an N-phenoxyalkyl moiety substituted at position 3 or 4 of the phenyl ring (1-9) and the other of N-alkenyl or alkinyl phthalimides (10-18) - were synthesized, evaluated for anticonvulsant activity and had their in silico lipophilicity estimated using computer programs. The anticonvulsant activity of phthalimides containing an unsaturated substituent at the phthalimide nitrogen was superior to that of the N-phenoxyalkyl phthalimides. Alkinyl derivative 10 emerged as the most active (in MES and ScMet tests) of all the compounds tested. A correlation between anticonvulsant activity and in silico estimated lipophilicity was not observed.
