1217351-41-1Relevant articles and documents
Molecular design of small organic molecules based on structural information for a conformationally constrained peptide that binds to G-CSF receptor
El-Haggar, Radwan,Kamikawa, Ken,Machi, Kazuya,Ye, Zhengmao,Ishino, Yuko,Tsumuraya, Takeshi,Fujii, Ikuo
supporting information; experimental part, p. 1169 - 1172 (2010/06/15)
Based on structural information for a peptide (P8-2KAQ) that binds to granulocyte-colony stimulating factor receptor (G-CSFR), small ligands with a biaryl scaffold were designed and their binding affinities were evaluated.