121743-65-5

Basic information

• Product Name: 2-(3-Butynylthio)-5-phenylpyrimidine
• Synonyms: 2-(3-Butynylthio)-5-phenylpyrimidine
• CAS NO: 121743-65-5
• Molecular Weight: 240.329
• Mol File: 121743-65-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-Butynylthio)-5-phenylpyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Butynylthio)-5-phenylpyrimidine(121743-65-5)
• EPA Substance Registry System: 2-(3-Butynylthio)-5-phenylpyrimidine(121743-65-5)

Safety Data

• Hazardous Substances Data: 121743-65-5(Hazardous Substances Data)

Upstream product

• 43001-25-8 4-iodobut-1-yne 
• 31408-19-2 2-mercapto-5-phenylpyrimidine 

Downstream Products

• 127238-06-6 2,3-Dihydro-1,1-dioxo-5-phenylthieno<2,3-b>pyridine 
• 127237-97-2 2,3-Dihydro-5-phenyl-1-oxothieno<2,3-b>pyridine 
• 127237-79-0 2-(3-Butynylsulfonyl)-5-phenylpyrimidine 
• 127237-78-9 2-(3-Butynylsulfinyl)-5-phenylpyrimidine 
• 121743-67-7 2,3-Dihydro-5-phenylthieno<2,3-b>pyridine 

Relevant articles and documents

RING-TRANSFORMATIONS OF PYRIMIDINES BY INTRAMOLECULAR DIELS-ALDER REACTIONS. SYNTHESIS OF ANNELATED PYRIDINES

Pyrimidines carrying an ω-alkyne side-chain -XCH2CH2CCH (X=O,N,S,SO,SO2) at the 2 or 5 position undergo intramolecular inverse electron demand Diels-Alder reactions across the C-2 and C-5 positions; elimination of hydrogen (or alkyl) cyanide from the intermediate adducts leads to condensed pyridines.The influence of the hetero atom (X) in the dienophilic side-chain and that of substituents in the pyrimidine ring on the reactivity is discussed.