1217435-87-4Relevant academic research and scientific papers
Acid catalyzed halogen dance on deactivated pyrroles
Tutino, Federico,Papeo, Gianluca,Quartieri, Francesca
, p. 112 - 117 (2010)
(Chemical Equation Presented) A study on the acid catalyzed halogen dance (ACHD) on deactivated bromopyrroles is reported. A different behavior is observed when considering singly deactivated pyrrole alkylcarboxamides, or doubly deactivated pyrroleketo-lactams (aldisines). Although less electron deficient pyrrole alkylcarboxamides suffer from ACHD, the double deactivation on keto-lactams disfavors pyrrole ring protonation thus preventing halogen scrambling. The mechanism involved in the rearrangement is hypothesized.
