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1217512-17-8

1217512-17-8

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1217512-17-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1217512-17-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,5,1 and 2 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1217512-17:
(9*1)+(8*2)+(7*1)+(6*7)+(5*5)+(4*1)+(3*2)+(2*1)+(1*7)=118
118 % 10 = 8
So 1217512-17-8 is a valid CAS Registry Number.

1217512-17-8Downstream Products

1217512-17-8Relevant articles and documents

N-Acetamideindolecarboxylic acid allosteric 'finger-loop' inhibitors of the hepatitis C virus NS5B polymerase: discovery and initial optimization studies

Beaulieu, Pierre L.,Jolicoeur, Eric,Gillard, James,Brochu, Christian,Coulombe, Rene,Dansereau, Nathalie,Duan, Jianmin,Garneau, Michel,Jakalian, Araz,Kuehn, Peter,Lagace, Lisette,LaPlante, Steven,McKercher, Ginette,Perrault, Stephane,Poirier, Martin,Poupart, Marc-Andre,Stammers, Timothy,Thauvette, Louise,Thavonekham, Bounkham,Kukolj, George

scheme or table, p. 857 - 861 (2010/09/18)

SAR studies at the N1-position of allosteric indole-based HCV NS5B inhibitors has led to the discovery of acetamide derivatives with good cellular potency in subgenomic replicons (EC50 200 nM). This class of inhibitors displayed improved physicochemical properties and favorable ADME-PK profiles over previously described analogs in this class.

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