1217554-42-1

Basic information

• Product Name: 1-(4-(4-methoxyphenyl)buta-1,3-diynyl)-3-methylbenzene
• Synonyms: 1-(4-(4-methoxyphenyl)buta-1,3-diynyl)-3-methylbenzene
• CAS NO: 1217554-42-1
• Molecular Weight: 246.309
• Mol File: 1217554-42-1.mol

Chemical Properties

• CAS DataBase Reference: 1-(4-(4-methoxyphenyl)buta-1,3-diynyl)-3-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(4-methoxyphenyl)buta-1,3-diynyl)-3-methylbenzene(1217554-42-1)
• EPA Substance Registry System: 1-(4-(4-methoxyphenyl)buta-1,3-diynyl)-3-methylbenzene(1217554-42-1)

Safety Data

• Hazardous Substances Data: 1217554-42-1(Hazardous Substances Data)

Upstream product

• 29835-27-6 3-(3-methylphenyl)prop-2-ynoic acid 
• 768-60-5 4-methoxyphenylacetylen 
• 766-82-5 1-ethynyl-3-methyl-benzene 

Relevant articles and documents

An efficient approach to homocoupling of terminal alkynes: Solvent-free synthesis of 1,3-diynes using catalytic Cu(II) and base

We report an environmentally friendly, efficient method for transforming terminal acetylenes into 1,3-diynes based on catalytic amounts of a Cu(ii) salt and base under solvent-free conditions. The developed process conforms to the principles of 'green' chemistry and addresses the shortage of such methods for the synthesis of 1,3-diynes. The reaction is quite general and results in good yields. Interestingly, the system also allows the synthesis of unsymmetric 1,3-diynes by cross-coupling of two different terminal alkynes. Finally, the catalyst can also be recycled.

Recyclable Cu/C3N4 composite catalysed homo- and cross-coupling of terminal alkynes under mild conditions

A Cu/C3N4 composite was prepared and utilized as a highly efficient and environmentally friendly catalyst for the homo- & cross-coupling of terminal alkynes. Excellent functional group tolerance and good yields were observed with oxygen as an oxidant in an isopropanol solution (or as additive) under ambient conditions. Furthermore, the composite catalyst shows good recyclability and can be recovered simply and reused several times without significant loss in its catalytic activities.

Iron/copper promoted oxidative homo-coupling reaction of terminal alkynes using air as the oxidant

An inexpensive catalytic system, which used a readily available Fe(acac)3 and trace quantity of Cu(acac)2 as the co-catalyst and air as the oxidant for the homo-coupling of terminal alkynes, has been developed. The catalytic system could also apply to the cross-coupling reaction of two different terminal alkynes.

Copper-catalyzed decarboxylative cross-coupling of propiolic acids and terminal alkynes

A copper-catalyzed decarboxylative cross-coupling reaction of propiolic acids with terminal alkynes is developed leading to unsymmetric 1,3-conjugated diynes under mild conditions. This method provides a novel decarboxylative cross-coupling for sp-sp bond formation. Compared to organic halides, only carbon dioxide is produced as by-products in this approach.