1217603-26-3 Usage
General Description
FMOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID is a chemical compound that contains an FMOC (9-fluorenylmethyloxycarbonyl) protecting group attached to a 2R,3R-3-amino-2-hydroxy-5-methylhexanoic acid moiety. FMOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID is commonly used in peptide synthesis as a building block for the creation of peptides with specific sequences and properties. The FMOC group serves to protect the amine group on the amino acid, allowing for selective deprotection and coupling reactions during peptide assembly. The 2R,3R-3-amino-2-hydroxy-5-methylhexanoic acid moiety provides a chiral center, making this compound useful for the synthesis of chiral peptides and related compounds. Overall, FMOC-(2R,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID is an important chemical tool for the production of diverse peptide-based molecules in the field of biochemistry and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1217603-26-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,6,0 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1217603-26:
(9*1)+(8*2)+(7*1)+(6*7)+(5*6)+(4*0)+(3*3)+(2*2)+(1*6)=123
123 % 10 = 3
So 1217603-26-3 is a valid CAS Registry Number.
1217603-26-3Relevant articles and documents
Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitors
Hattori, Yasunao,Kobayashi, Kazuya,Deguchi, Ayaka,Nohara, Yukie,Akiyama, Tomomi,Teruya, Kenta,Sanjoh, Akira,Nakagawa, Atsushi,Yamashita, Eiki,Akaji, Kenichi
, p. 5626 - 5640 (2015/11/11)
A superior substrate sequence for BACE1 containing transition-state mimics at the scissile site was evaluated as a protease inhibitor. Hydroxymethylcarbonyl (HMC) and hydroxyethylamine (HEA) isosteres were selected as the transition state mimics, and inco
Chemoenzymatic synthesis of Fmoc-protected (2S,3S)-2-hydroxy-3-amino acids and their application in the synthesis of an α-hydroxylated β-hexapeptide
Tromp, Reynier A.,Van der Hoeven, Michael,Amore, Alessia,Brussee, Johannes,Overhand, Mark,Van der Marel, Gijs A.,Van der Gen, Arne
, p. 1109 - 1112 (2007/10/03)
A chemoenzymatic and stereoselective synthesis of Fmoc-protected (2S,3S)-2-hydroxy-3-amino acids from 2-furaldehyde is described as well as their application, without prior hydroxyl protection, in the solid-phase synthesis of a novel completely α-hydroxylated β-hexapeptide.
