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1217630-38-0

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1217630-38-0 Usage

General Description

"(2S)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE" is a chemical compound that belongs to the class of organic compounds known as aryl fluorides. These are aromatic compounds containing a fluorine atom linked to an aromatic group. It specifically has a Pyrrolidine ring structure, a common feature in many natural products, including alkaloids and antibiotics. The "2S" denotes the specific arrangement or orientation of atoms within the molecule. (2S)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE has the presence of two fluorine atoms on its phenyl ring, at the 2nd and 5th positions. Its characteristics and properties may vary depending upon its reactive groups, but detailed specifics about its uses and other properties are not widely documented or well-known.

Check Digit Verification of cas no

The CAS Registry Mumber 1217630-38-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,6,3 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1217630-38:
(9*1)+(8*2)+(7*1)+(6*7)+(5*6)+(4*3)+(3*0)+(2*3)+(1*8)=130
130 % 10 = 0
So 1217630-38-0 is a valid CAS Registry Number.

1217630-38-0Relevant articles and documents

Efficient preparation of (R)-2-(2,5-difluorophenyl)pyrrolidine via a recycle process of resolution

Lv, Xunlei,Chen, Liang,Pan, Jing,Meng, Xue,Bi, Siju,Liu, Weiyuan,Zhou, Ting,Lin, Kuaile,Ye, Deyong,Zhou, Weicheng

, p. 931 - 937 (2021/10/19)

An efficient preparation of (R)-2-(2,5-difluorophenyl)pyrrolidine ((R)-1) from the racemate based on a recycle process of resolution/racemization was described. In the process, the desired (R)-1 was obtained by resolution with D-malic acid in 95% EtOH. Me

FIVE-AND-SIX-MEMBERED HETEROCYCLIC COMPOUND AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITOR

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Paragraph 0060; 0065-0066, (2021/12/18)

A class of five-membered fused with six-membered heterocyclic compounds represented by formula I and a pharmaceutical composition, preparation, and an application thereof are disclosed. These compounds have TRK kinase inhibitory activity and can treat diseases related to TRK dysfunction.

SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR

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Paragraph 0078; 0083-0084, (2021/09/24)

Provided are a preparation and applications of a six-membered fused with six-membered heterocyclic compound, specifically, provided in the present invention is a compound as represented by formula I as follows, where the definitions of the groups are as described in the description. The compound has TRK kinase inhibiting activity and can serve as a pharmaceutical composition for treating TRK dysfunction-related diseases.

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