121767-99-5Relevant articles and documents
Synthesis of the Aromatase Inhibitor 3-Ethyl-3-(4-pyridyl)piperidine-2,6-dione and Its Enantiomers
McCague, Raymond,Jarman, Michael,Rowlands, Martin G.,Mann, John,Thickitt, Christopher P.,et al.
, p. 196 - 198 (2007/10/02)
Convenient syntheses of (R/S)-3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (pyridoglutethimide) and its enantiomers are described; aromatase inhibitory activity was almost entirely confined to the 3R-enantiomer