1217726-49-2

Basic information

• Product Name: (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(1-NAPHTHYLOXY)-2-PYRROLIDINECARBOXYLIC ACID
• Synonyms: (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(1-NAPHTHYLOXY)-2-PYRROLIDINECARBOXYLIC ACID;1,2-Pyrrolidinedicarboxylic acid, 4-(1-naphthalenyloxy)-, 1-(1,1-dimethylethyl) ester, (2R,4R)-rel-
• CAS NO: 1217726-49-2
• Molecular Formula: C20H23NO5
• Molecular Weight: 357.4
• Mol File: 1217726-49-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 537.4±50.0 °C(Predicted)
• Appearance: /
• Density: 1.263±0.06 g/cm3(Predicted)
• PKA: 3.69±0.40(Predicted)
• CAS DataBase Reference: (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(1-NAPHTHYLOXY)-2-PYRROLIDINECARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(1-NAPHTHYLOXY)-2-PYRROLIDINECARBOXYLIC ACID(1217726-49-2)
• EPA Substance Registry System: (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-(1-NAPHTHYLOXY)-2-PYRROLIDINECARBOXYLIC ACID(1217726-49-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 1217726-49-2(Hazardous Substances Data)

Upstream product

• 74844-91-0 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 
• 90-15-3 α-naphthol 
• 630425-44-4 boc-((4R)-naphthal-1-oxo)-Pro-OMe 

Relevant articles and documents

Inhibitors of Hepatitis C Virus

Macrocyclic peptides are disclosed having the general formula: wherein R3, R3′, R4, R6, R′, X, Q and W are described. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Inhibitors of Hepatitis C Virus

Macrocyclic peptides are disclosed having the general formula: wherein R3, R3′, R4, R6, R′, X, Q and W are described. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Hepatitis C virus inhibitors

The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which inhibit the function of the NS3 protease (also referred to herein as “serine protease”) encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS3 protease.