1217746-74-1 Usage
Description
N-(2-Mercaptoethyl) Demecolcine is a chemical compound that functions as an antimitotic agent. It is a yellow solid with the ability to disrupt microtubules by binding to tubulin and preventing its polymerization. N-(2-MERCAPTOETHYL) DEMECOLCINE also stimulates the intrinsic GTPase activity of tubulin and induces apoptosis in several normal and tumor cell lines. Additionally, it activates the JNK/SAPK signaling pathway.
Uses
Used in Pharmaceutical Industry:
N-(2-Mercaptoethyl) Demecolcine is used as an antimitotic agent for its ability to disrupt microtubules and prevent tubulin polymerization. This property makes it a potential candidate for the development of drugs targeting cancer cells, as it can inhibit their growth and proliferation.
Used in Cancer Research:
In cancer research, N-(2-Mercaptoethyl) Demecolcine is used to study the effects of microtubule disruption on tumor cell lines. Its ability to induce apoptosis and activate the JNK/SAPK signaling pathway makes it a valuable tool for understanding the mechanisms of cell death and potential therapeutic targets in cancer treatment.
Used in Drug Development:
N-(2-Mercaptoethyl) Demecolcine is used in drug development as a starting point for designing new compounds with improved efficacy and reduced side effects. Its unique properties, such as stimulating the intrinsic GTPase activity of tubulin, can be leveraged to create novel therapeutic agents for the treatment of various diseases, including cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1217746-74-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,7,4 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1217746-74:
(9*1)+(8*2)+(7*1)+(6*7)+(5*7)+(4*4)+(3*6)+(2*7)+(1*4)=161
161 % 10 = 1
So 1217746-74-1 is a valid CAS Registry Number.
