1217792-53-4Relevant articles and documents
New 1-aryl-3-substituted propanol derivatives as antimalarial agents
Perez-Silanes, Silvia,Berrade, Luis,Garcia-Sanchez, Rory N.,Mendoza, Adela,Galiano, Silvia,Perez-Solorzano, Berta Martin,Nogal-Ruiz, Juan J.,Martinez-Fernandez, Antonio R.,Aldana, Ignacio,Monge, Antonio
experimental part, p. 4120 - 4135 (2010/03/04)
This paper describes the synthesis and in vitro antimalarial activity against a P. falciparum 3D7 strain of some new 1-aryl-3-substituted propanol derivatives. Twelve of the tested compounds showed an IC50 lower than 1 μM. These compounds were