1217817-71-4Relevant academic research and scientific papers
Room temperature cross-coupling of highly functionalized organozinc reagents with thiomethylated N-heterocycles by nickel catalysis
Melzig, Laurin,Metzger, Albrecht,Knochel, Paul
supporting information; experimental part, p. 2131 - 2133 (2010/06/12)
Chemical Equation Presented A variety of thiomethyl-substituted N-heterocycles such as pyridines, isoquinolines, pyrimidines, pyrazines, pyridazines, quinazolines, triazines, benzothiazoles, or benzoxazoles undergo smooth Ni-catalyzed cross-coupling reactions with functionalized aryl-, heteroaryl-, alkyl-, and benzylic zinc reagents using an inexpensive Ni(acac)2/ DPE-Phos catalytic system at 25°C.
