121783-39-9

Upstream product

• 26394-25-2 (E)-4-chloro-2-methylbut-2-enal 
• 873-55-2 sodium benzenesulfonate 
• 69690-06-8 4-formyl-3-methyl-2-butenyl phenyl sulfide 
• 503-60-6 3,3-dimethyl-allyl chloride 
• 15874-80-3 3-methyl-1-(phenylsulfonyl)but-2-ene 

Downstream Products

• 121783-35-5 (S)-2-methyl-4-phenylsulfonylbutanoic acid 
• 1606991-74-5 [(4E,6E)-6-(2,2-dimethylhydrazono)-5-methyl-3-(phenylsulfonyl)hex-4-en-2-ol] 
• 1606991-75-6 (E)-1,1-dimethyl-2-[(E)-2-methyl-4-(phenylsulfonyl)pent-2-enylidene]hydrazine 
• 1606991-76-7 (2E,2′E)-2,2′-{(2E,2′E,6E,6′E)-8,8′-sulfonylbis[2,6-dimethyl-4-(phenylsulfonyl)octa-2,6-dien-8-yl-1-ylidene]}bis(1,1-dimethylhydrazine) 
• 1606991-68-7 (E)-5,5-dimethyl-2-[4-(phenylsulfonyl)but-2-en-2-yl]-1,3-dioxane 
• 1606991-72-3 (E)-1,1-dimethyl-2-[(E)-2-methyl-4-(phenylsulfonyl)but-2-enylidene]hydrazine 
• 73833-88-2 (E)-4-Benzenesulfonyl-2-methyl-pent-2-enal 
• 73833-89-3 ((1E,3E)-4-Ethoxy-3-methyl-buta-1,3-diene-1-sulfonyl)-benzene 
• 121783-43-5 (S)-4-Benzenesulfonyl-2-methyl-butyric acid methyl ester 

Relevant academic research and scientific papers

C5 SULFONE COMPOUND, METHOD FOR PREPARING THE SAME, METHOD FOR PREPARING CROCETIN DINITRILE USING THE SAME, AND USE THEREOF

The present invention relates to a novel C5 sulfone compound, a method for preparing same, and a method for producing a crocetin dinitrile compound and, more specifically, to a novel C5 sulfone compound having a hydrazone protective group, a method for preparing same, and a method for efficiently producing a crocetin dinitrile compound using the same. The novel sulfone compound in accordance with the present invention is stable and excellent in crystallization, and thus easy to be separated and purified, and to form E-structure in the case of forming a double bond. In addition, since sulfinic acid, which is a by-product of the bonding, is easily removed in the case of synthesizing crocetin dinitrile by using the sulfone compound, a pure final product can be efficiently obtained. The crocetin dinitrile compound in accordance with the present invention is a kind of carotene compounds, and has nitrile groups on both ends thereof, thus various types of reactivity are expectable. In addition, a nitrogen atom contained in both ends of the compound has high affinity with metals, thereby enabling self-assembly on the surface of the metal. Furthermore, the crocetin dinitrile compound can exhibit a general antioxidative activity of the carotene, and can be used as an electrical and electronic material such as an organic molecular wire or the like.COPYRIGHT KIPO 2016

Sulfone-mediated syntheses of crocetin derivatives: Regioselectivity of highly functionalized building blocks

New C5 sulfone building blocks containing a masked polar end group have been devised for the efficient synthesis of carotenoids with polar termini. Chemoselectivity or the regiochemical issue of the highly functionalized units has been carefully addressed depending on the soft or hard nature of electrophiles. These building blocks have been successfully applied to the syntheses of crocetin derivatives, crocetin dial and the novel crocetin dinitrile.

Selective oxidation of allylic sulfides by hydrogen peroxide with the trirutile-type solid oxide catalyst LiNbMoO6

Chemoselective sulfur oxidation of allylic sulfides containing double bonds of high electron density due to multiple alkyl substituents or extended conjugation was developed using the composite metal oxide catalyst, LiNbMoO6, without any epoxidation of the electron-rich double bond(s). Selective oxidation to either the corresponding sulfoxides or the sulfones was realized by controlling the stoichiometry of the quantitative oxidant, H202. This new oxidant system had general applicability for chemoselective oxidation of various allylic, benzylic, or propargylic sulfides containing unsaturated carbon-carbon bonds with different electron properties. Various functional groups including hydroxy, formyl, and ethers of THP or TBDMS are compatible under this mild oxidation reaction condition.

PREPARATION OF CHIRAL C5-BUILDING BLOCKS FOR TERPENE SYNTHESIS BY BAKERS' YEAST REDUCTION OF SULFUR-FUNCTIONALIZED PRENYL DERIVATIVES

Enantioselective hydrogenation of several α,β-unsaturated aldehydes and allylic alcohols of sulfur-functionalized prenyl derivatives with bakers' yeast gave bifunctional chiral (S)- and (R)-C5-building blocks for terpene synthesis with high enantiomeric e

γ-Alkylation of α,β-Unsaturated Ketones. γ-Arylsulfonyl Groups as Regioselective Control Elements

A reaction sequence for γ-alkylation of α,β-unsaturated ketones has been proposed and tested with some success. γ-(Phenylsulfonyl) groups are (1) introduced into the substrate; (2) present during alkylation of the resulting highly delocalized carbanions; (3) finally removed to leave the otherwise inaccessible γ-alkylation product.