Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1217840-61-3

FMoc-N-Me-His(Trt)-OH, also known as Fmoc-His(Trt)-OH, is a derivative of the amino acid histidine that is primarily used in peptide synthesis. It is protected by the Fmoc (9-fluorenylmethoxycarbonyl) group, which prevents it from reacting with other amino acids until it is purposely removed in a later step of synthesis. The Trt (Trityl) group specifically protects the imidazole side chain of histidine. Methylation (the addition of a methyl or -CH3 group) increases the compound’s hydrophobicity, improving its solubility in organic solvents. The “OH” indicates the presence of a hydroxyl group, which often acts as the reactive site in peptide synthesis.

1217840-61-3 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

  • N-α-(9-Fluorenylmethoxycarbonyl)-N-α-methyl-N-τ-trityl-L-histidine

    Cas No: 1217840-61-3

  • No Data

  • No Data

  • No Data

  • BOC Sciences
  • Contact Supplier
  • 1217840-61-3 Structure

  • Basic information

    1. Product Name: FMoc-N-Me-His(Trt)-OH
    2. Synonyms: FMoc-N-Me-His(Trt)-OH;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-1-(triphenylmethyl)-L-histidine;(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanoic acid;(9H-Fluoren-9-yl)MethOxy]Carbonyl N-Me-His(Trt)-OH
    3. CAS NO:1217840-61-3
    4. Molecular Formula: C41H35N3O4
    5. Molecular Weight: 633.75
    6. EINECS: N/A
    7. Product Categories: amino acids
    8. Mol File: 1217840-61-3.mol

  • Chemical Properties

    1. Melting Point: 183-188°C
    2. Boiling Point: 793.8±60.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.21±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 3.07±0.10(Predicted)
    10. CAS DataBase Reference: FMoc-N-Me-His(Trt)-OH(CAS DataBase Reference)
    11. NIST Chemistry Reference: FMoc-N-Me-His(Trt)-OH(1217840-61-3)
    12. EPA Substance Registry System: FMoc-N-Me-His(Trt)-OH(1217840-61-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1217840-61-3(Hazardous Substances Data)

1217840-61-3 Usage

Uses

Used in Pharmaceutical Industry:
FMoc-N-Me-His(Trt)-OH is used as a building block for the synthesis of peptides and proteins for various therapeutic applications. Its protection groups ensure controlled and selective reactions during the synthesis process, leading to the formation of complex peptide structures with desired properties.
Used in Research and Development:
FMoc-N-Me-His(Trt)-OH is used as a research tool for studying the properties and interactions of histidine-containing peptides and proteins. FMoc-N-Me-His(Trt)-OH's unique structure allows scientists to investigate the effects of histidine methylation and protection on peptide folding, stability, and biological activity.
Used in Diagnostic Applications:
FMoc-N-Me-His(Trt)-OH can be used in the development of diagnostic assays and tests that rely on the specific recognition and binding of histidine-containing peptides or proteins. FMoc-N-Me-His(Trt)-OH's protected structure enables the creation of stable and sensitive diagnostic reagents.
Used in Drug Delivery Systems:
FMoc-N-Me-His(Trt)-OH can be incorporated into drug delivery systems, such as nanoparticles or hydrogels, to improve the solubility, stability, and targeted delivery of therapeutic peptides and proteins. FMoc-N-Me-His(Trt)-OH's hydrophobicity and reactivity can be tailored to enhance the performance of these systems.

Check Digit Verification of cas no

The CAS Registry Mumber 1217840-61-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,8,4 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1217840-61:
(9*1)+(8*2)+(7*1)+(6*7)+(5*8)+(4*4)+(3*0)+(2*6)+(1*1)=143
143 % 10 = 3
So 1217840-61-3 is a valid CAS Registry Number.

1217840-61-3 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail

  • Aldrich

  • (773093)  Fmoc-N-Me-His(Trt)-OH  95%

  • 1217840-61-3

  • 773093-250MG

  • 2,172.69CNY

  • Detail

  • Aldrich

  • (773093)  Fmoc-N-Me-His(Trt)-OH  95%

  • 1217840-61-3

  • 773093-1G

  • 5,914.35CNY

  • Detail

1217840-61-3Upstream product

1217840-61-3Downstream Products

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1217840-61-3