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rac Biotin-d4, also known as (+/-)-Biotin-d4, is a stable isotope-labeled form of biotin, a water-soluble vitamin and growth factor present in minute amounts in every living cell. It plays an indispensable role in numerous naturally occurring carboxylation reactions and occurs mainly bound to proteins or polypeptides. The richest sources of biotin are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue. rac Biotin-d4 is an off-white solid and is used as a valuable tool in various applications due to its stable isotope labeling.

1217850-77-5

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1217850-77-5 Usage

Uses

Used in Biochemical Research:
rac Biotin-d4 is used as a biochemical research tool for studying the mechanisms of carboxylation reactions and the role of biotin in various metabolic pathways. Its stable isotope labeling allows for accurate tracking and quantification of biotin in complex biological systems.
Used in Mass Spectrometry:
In mass spectrometry, rac Biotin-d4 is used as an internal standard for the accurate quantification of biotin and its metabolites. The stable isotope labeling of rac Biotin-d4 provides a reliable reference point for mass spectrometry analysis, improving the accuracy and precision of biotin measurements.
Used in Drug Metabolism Studies:
rac Biotin-d4 is used in drug metabolism studies to investigate the role of biotin in the metabolism and disposition of various drugs and compounds. Its stable isotope labeling allows for the tracking of biotin-related metabolic pathways and the identification of potential drug-drug interactions.
Used in Nutritional Analysis:
In nutritional analysis, rac Biotin-d4 is used as a tracer to study the bioavailability and absorption of biotin from various food sources. The stable isotope labeling of rac Biotin-d4 enables the accurate measurement of biotin intake and its subsequent distribution in the body.
Used in Cancer Research:
rac Biotin-d4 is used in cancer research to investigate the higher biotin content in cancerous tumors compared to normal tissue. The stable isotope labeling of rac Biotin-d4 allows for the tracking of biotin in tumor cells and the study of its potential role in cancer progression and metastasis.
Used in Pharmaceutical Development:
In pharmaceutical development, rac Biotin-d4 is used as a labeled compound for the synthesis of biotin-based drugs and drug candidates. The stable isotope labeling of rac Biotin-d4 provides a means to track the pharmacokinetics and pharmacodynamics of these compounds, aiding in the optimization of drug efficacy and safety.

Check Digit Verification of cas no

The CAS Registry Mumber 1217850-77-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,8,5 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1217850-77:
(9*1)+(8*2)+(7*1)+(6*7)+(5*8)+(4*5)+(3*0)+(2*7)+(1*7)=155
155 % 10 = 5
So 1217850-77-5 is a valid CAS Registry Number.

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