1217902-86-7Relevant academic research and scientific papers
Dess-martin periodinane mediated intramolecular cyclization of phenolic azomethines: A solution-phase strategy toward benzoxazoles and benzothiazoles
Bose, D. Subhas,Idrees, Mohd.
, p. 398 - 402 (2010)
Dess-Martin periodinane (DMP), a highly versatile hypervalent iodine(V) reagent, was found to efficiently mediate the intramolecular cyclization of phenolic azomethines/Schiff bases at ambient temperature leading to the rapid and expeditious synthesis of substituted benzoxazoles and benzothiazoles. Furthermore, a solution-phase strategy has been developed by treating the reaction mixtures sequentially with Amberlyst A-26 thiosulfate resin and diisopropylaminomethyl resin (PS-DIEA), which remove excess reagent and byproducts, to give pure products. Georg Thieme Verlag Stuttgart - New York.
