1218780-09-6

Basic information

• Product Name: 3,3'-((4-(methylthio)phenyl)methylene)bis(1H-indole)
• Synonyms: 3,3'-((4-(methylthio)phenyl)methylene)bis(1H-indole)
• CAS NO: 1218780-09-6
• Molecular Weight: 368.502
• Mol File: 1218780-09-6.mol

Chemical Properties

• CAS DataBase Reference: 3,3'-((4-(methylthio)phenyl)methylene)bis(1H-indole)(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-((4-(methylthio)phenyl)methylene)bis(1H-indole)(1218780-09-6)
• EPA Substance Registry System: 3,3'-((4-(methylthio)phenyl)methylene)bis(1H-indole)(1218780-09-6)

Safety Data

• Hazardous Substances Data: 1218780-09-6(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 3446-89-7 4-(Methylthio)benzaldehyde 
• 3446-90-0 4-(methylthio)benzyl alcohol 

Relevant articles and documents

Synthesis, antibacterial and anti-inflammatory activity of bis(indolyl)methanes

A series of bioactive bis(indolyl)methanes are synthesized by one-pot green reaction of indole with various substituted aldehydes by microwave irradiation under solvent free conditions. The antibacterial activity against Staphylococcus aureus and anti-inf

Phosphine-Free Manganese(II)-Catalyst Enables Acceptorless Dehydrogenative Coupling of Alcohols with Indoles

Herein, an air-stable, molecularly defined NNN?Mn(II) pincer complex catalyzed acceptorless dehydrogenative coupling of alcohols with indoles is reported. A wide variety of symmetrical and unsymmetrical bis(indolyl)methane derivatives as well as some structurally important products such as Vibrindole A, Turbomycin B alkaloid, Antileukemic, and Anticancer agents were synthesized. Mechanistic studies illustrate the importance of the NH moiety in the complex and the crucial role of metal-ligand cooperation during catalysis. (Figure presented.).

A facile and efficient method for the synthesis of bis(indolyl)methanes catalyzed by selectfluorTMunder conventional heating and microwave irradiation

Electrophilic substitution reaction of indoles with different aldehydes was carried out using selectfluorTM as a catalyst which was resulted in the formation of bis (indolyl) methanes in good to excellent yields (72-96% The desired products were obtained by both conventional heating and microwave irradiation under solvent-free conditions.