1218786-99-2Relevant academic research and scientific papers
Microwave assisted synthesis of 1,3,4-oxadiazolyl 1, 8-naphthyridines under solvent-free conditions using solid support
Mogilaiah,Swamy, T. Kumara,Chandra, A. Vinay,Srivani
experimental part, p. 1462 - 1465 (2010/02/28)
A convient synthesis of 1-(4-acetyl-5-aryl-5-methyl-[1,3, 4]oxadiazol-2-ylmethyl)-3-(4-chlorophenyl)-1H-[1, 8]naphthyridin-2-ones, by cyclization of acetophenone [2-oxo-3-(4-chlorophenyl)-2H-[1,8]-naphthyridin-1 -yl]methylcarbonylhydrazones with acetic anhydride using silica gel as solid support under microwave irradition is described. The structural assignments of the compounds are based on their elemental analyses and spectral data.
