1218818-70-2Relevant academic research and scientific papers
A convenient two-step synthesis of 2-arylbenzofurans
Duan, Xin-Fang,Feng, Jian-Xia,Zhang, Zhan-Bin
experimental part, p. 515 - 519 (2010/06/11)
A novel and convenient two-step synthesis of 2-arylbenzofurans is described which proceeds via a selective cross-pinacol-type coupling between a salicylaldehyde and an aromatic aldehyde, followed by an acid-promoted cyclization. One advantage of this method is that separation of the three possible pinacol products that can form during the cross-coupling is not necessary. This method is also applied to the synthesis of the 2-arylbenzofuran-containing natural product, homoegonol.
