1218818-87-1

Basic information

• Product Name: 5-chloro-2-phenylfuro[3,2-h]quinoline
• Synonyms: 5-chloro-2-phenylfuro[3,2-h]quinoline
• CAS NO: 1218818-87-1
• Molecular Weight: 279.725
• Mol File: 1218818-87-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-chloro-2-phenylfuro[3,2-h]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-phenylfuro[3,2-h]quinoline(1218818-87-1)
• EPA Substance Registry System: 5-chloro-2-phenylfuro[3,2-h]quinoline(1218818-87-1)

Safety Data

• Hazardous Substances Data: 1218818-87-1(Hazardous Substances Data)

Upstream product

• 130-26-7 5-chloro-7-iodoquinolin-8-ol 
• 536-74-3 phenylacetylene 

Downstream Products

• 1436840-89-9 5-chloro-9-(2-oxo-2-phenyl-ethyl)-2-phenyl-furo[3,2-h]quinolin-9-ium bromide 
• 1436841-33-6 10-benzoyl-5-chloro-2-phenyl-1-oxa-10a-aza-dicyclopenta[a,h]naphthalene-8-carboxylic acid methyl ester 
• 1436841-28-9 10-benzoyl-5-chloro-2-(4-fluoro-phenyl)-1-oxa-10a-aza-dicyclopenta[a,h]naphthalene-8-carboxylicacid ethyl ester 
• 1436841-23-4 10-benzoyl-5-chloro-2-phenyl-1-oxa-10a-aza-dicyclopenta[a,h]naphthalene-8,9-dicarboxylic acid diethyl ester 
• 1436841-19-8 10-benzoyl-5-chloro-2-phenyl-1-oxa-10a-aza-dicyclopenta[a,h]naphthalene-8,9-dicarboxylic acid dimethyl ester 

Relevant articles and documents

A green approach for highly regioselective syntheses of furo[3,2-h]quinolines in aqueous medium

An environmentally benign, high yielding, and operationally simple protocol has been developed for the regioselective synthesis of furo[3,2-h]quinolines in aqueous micellar medium involving Cu-free domino Sonogashira reaction followed by 5-endo-dig-cyclization of substituted 8-hydroxyquinolines and terminal alkyne by using Pd(C6H5CN)Cl2 as catalyst and 2-pyridinecarboxaldehyde methylphenyl hydrazone as ligand under aerobic condition.

One-pot tandem synthesis of Furo[3,2- h ]quinolines by a sonogashira cross-coupling and cyclization reaction supported by basic alumina under microwave irradiation

Acetylenic 8-quinolinols generated in situ by the Sonogashira cross-coupling reaction are efficiently converted into furo[3,2-h]quinolines by microwave-assisted, copper-catalyzed, intramolecular cyclization in the presence of basic alumina. Georg Thieme Verlag Stuttgart New York.