1218944-71-8

Upstream product

• 38496-18-3 2,6-dichloropyridine-3-carboxylic acid 
• 1218944-59-2 6-chloro-2-(2,2-difluoro-ethoxy)-nicotinic acid 
• 1218944-61-6 6-chloro-2-(2,2-difluoro-ethoxy)-nicotinic acid methyl ester 
• 1218944-63-8 6-chloro-2-(2,2-difluoro-ethoxy)-5-nitro-nicotinic acid methyl ester 
• 1218944-65-0 2-(2,2-difluoro-ethoxy)-6-methylamino-5-nitro-nicotinic acid methyl ester 
• 1218944-66-1 2-(2,2-difluoro-ethoxy)-6-methylamino-5-nitro-nicotinic acid 
• 1218944-68-3 N-(4-bromo-phenyl)-2-(2,2-difluoro-ethoxy)-6-methylamino-5-nitro-nicotinamide 

Downstream Products

• 1360702-29-9 N-(4-chloro-3-{N'-[3-(4-bromo-phenylcarbamoyl)-2-(2,2-difluoro-ethoxy)-6-methylamino-pyridin-5-yl]-thioureido}-benzyl)-2,2-dimethyl-propionamide 
• 1360699-14-4 N-{4-chloro-3-[6-(4-bromo-phenylcarbamoyl)-5-(2,2-difluoro-ethoxy)-3-methyl-3H-imidazo[4,5-b]pyridin-2-ylamino]-benzyl}-2,2-dimethyl-propionamide 

Relevant academic research and scientific papers

2-(ARYLAMINO)-3H-IMIDAZO[4,5-B]PYRIDINE-6-CARBOXAMIDE DERIVATIVES AND THEIR USE AS MPGES-1 INHIBITORS

This invention relates to compounds of formula (I) their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of

NEW COMPOUNDS

This invention relates to compounds of formula I their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of i