121898-41-7Relevant academic research and scientific papers
Competing 1,n-elimination reactions of 1-bromo-5-bromomethyl-6,6-dichlorobicyclo[3.1.0]hexane: A strained 1,3-bridged cyclopropene and a vinylcarbene as reactive intermediates
Weber, Juergen,Brinker, Udo H.
, p. 14641 - 14650 (1996)
1-Bromo-5-bromomethyl-6,6-dichlorobicyclo[3.1.0]hexane (9) was treated with alkyllithium at different temperatures. After halogen metal exchange in 9, two competing 1,n-elimination reactions take place. A 1,2-elimination of organolithium compound 12 leads to strained 1,3-bridged cyclopropene 10 which undergoes a cyclopropene-vinylcarbene rearrangement to 17. Insertion of 17 into the ether solvent affords isomers 18a and 18b. In contrast, 1,4-eliminations of organolithium compound 13 generate butadienes 14 and 16, respectively. The formation of the products is temperature dependent.
A new general synthesis of annulated 1,2,3-triazoles using tandem Sonogashira-CuAAC reaction
Rakshit, Moumita,Kar, Gandhi K.,Chakrabarty, Manas
, p. 1681 - 1688 (2015)
A number of novel, fused 1,2,3-triazoles have been synthesized efficiently by the palladium(0)-copper(I)-catalyzed intramolecular heteroannulation of 2-/1-azidomethyl-1-/2-bromodihydro-naphthalenes, -arene and -cycloalkenes with terminal alkynes involving
Palladium-catalyzed cyclization/cyclopropanation reaction for the synthesis of fused N-containing heterocycles
Nandi, Sukla,Ray, Jayanta K.
scheme or table, p. 6993 - 6997 (2010/02/27)
Palladium-catalyzed cyclization/cyclopropanation can be used to convert a range of substituted cyclic N-aryl allyl/methallyl amines efficiently and selectively to the corresponding fused tetrahydropyridine/cyclopropane-fused isoquinoline derivatives via β
ENOLATE ALKYLATION OF BICYCLOOCT-5-EN-2-ONE AND RADICAL CYCLISATION - A POTENTIAL APPROACH FOR THE CONSTRUCTION OF TRICYCLIC CARBOCYCLES
Rajamannar, Thennati,Balasubramanian,Kalpattu Kuppuswamy
, p. 5789 - 5792 (2007/10/02)
The alkylation of bicyclooct-5-en-2-one (1) and intramolecular radical cyclisation towards the synthesis of functionalised tricyclic carbocycles - is reported.
