1218988-68-1

Basic information

• Product Name: (R)-1-(3-(naphthalen-2-yl)-3-oxopropyl)-2-oxocyclohexanecarbonitrile
• CAS NO: 1218988-68-1
• Molecular Weight: 305.376
• Mol File: 1218988-68-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(3-(naphthalen-2-yl)-3-oxopropyl)-2-oxocyclohexanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(3-(naphthalen-2-yl)-3-oxopropyl)-2-oxocyclohexanecarbonitrile(1218988-68-1)
• EPA Substance Registry System: (R)-1-(3-(naphthalen-2-yl)-3-oxopropyl)-2-oxocyclohexanecarbonitrile(1218988-68-1)

Safety Data

• Hazardous Substances Data: 1218988-68-1(Hazardous Substances Data)

Upstream product

• 4452-06-6 1-(naphthalen-2-yl)prop-2-en-1-one 
• 4513-77-3 2-cyanocyclohexanone 

Relevant articles and documents

Catalytic asymmetric conjugate addition of α-cyanoketones for the construction of a quaternary stereogenic center

(Figure Presented) The catalytic asymmetric conjugate addition of a-cyanoketone pronucleophiles to vinyl ketones promoted by a Y/1 catalyst is described. High enantioselectivity was observed for a range of aromatic vinyl ketones, providing 1,5-dicarbonyl compounds bearing an all-carbon quaternary stereogenic center. The product was successfully converted to a spiro-piperidine entity and a bicyclo[3.3.0]octane framework through either the reduction of nitrile or intramolecular pinacol coupling.