1219002-20-6Relevant academic research and scientific papers
Synthetic aromatic amino acids from a negishi cross-coupling reaction
Suhartono, Marcel,Schneider, Angelika E.,Duerner, Gerd,Goebel, Michael W.
, p. 293 - 303 (2010)
An N,O-protected, iodinated bishomoalanine derivative, safely available from glutamic acid, reacts with aryl halides in a Negishi reaction in high yields. From the coupling product, Fmoc-protected amino acids with aromatic and heteroaromatic side chains were generated in high yields by racemization-free procedures. These monomers could be used for solid-phase peptide synthesis. Georg Thieme Verlag Stuttgart.
