1219002-52-4

Upstream product

• 1219002-42-2 3'-O-(tert-butyldiphenylsilyl)-(5'S)-C-(1-azidopent-3-enyl)-thymidine 
• 39735-76-7 1-iodo-4-(prop-2-yn-1-yloxy)benzene 

Downstream Products

• 1219002-43-3 (5'S)-C-(1-(pent-3-enyl)-(4-(4-iodophenoxy)methyl)-1H-1,2,3-triazol-1-yl)-thymidine 
• 1219002-63-7 C₆₁H₆₄IN₅O₈Si 

Relevant academic research and scientific papers

A 'click chemistry' approach to the efficient synthesis of modified nucleosides and oligonucleotides for PET imaging

Different thymidine derivatives bearing either an iodoaryl moiety at the 5′ position or a dialkylsilyl group at the 3′ position have been efficiently synthesized as precursors for carbon-11 or fluorine-18 labeling, respectively. Furthermore, iodoarylated thymidine derivatives have been incorporated into oligonucleotides giving an original way to label them with carbon-11.