1219004-75-7Relevant articles and documents
Structure based design of an in vivo active hydroxamic acid inhibitor of P. aeruginosa LpxC
Warmus, Joseph S.,Quinn, Cheryl L.,Taylor, Clarke,Murphy, Sean T.,Johnson, Timothy A.,Limberakis, Chris,Ortwine, Daniel,Bronstein, Joel,Pagano, Paul,Knafels, John D.,Lightle, Sandra,Mochalkin, Igor,Brideau, Roger,Podoll, Terry
, p. 2536 - 2543 (2012/05/20)
Lipid A is an essential component of the Gram negative outer membrane, which protects the bacterium from attack of many antibiotics. The Lipid A biosynthesis pathway is essential for Gram negative bacterial growth and is unique to these bacteria. The firs