1219010-20-4

Basic information

• Product Name: C₁₂H₆⁽²⁾H₅IN₂O
• Synonyms: C₁₂H₆⁽²⁾H₅IN₂O
• CAS NO: 1219010-20-4
• Molecular Weight: 331.097
• Mol File: 1219010-20-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₆⁽²⁾H₅IN₂O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₆⁽²⁾H₅IN₂O(1219010-20-4)
• EPA Substance Registry System: C₁₂H₆⁽²⁾H₅IN₂O(1219010-20-4)

Safety Data

• Hazardous Substances Data: 1219010-20-4(Hazardous Substances Data)

Upstream product

• 43019-90-5 benzoyl chloride-d5 
• 1219010-15-7 3-iodo-but-3-enyl-cyanamide 

Downstream Products

• 1219010-18-0 C₁₂H₁₀N₂O 
• 1867-37-4 Benzylmalononitrile 
• 98262-85-2 3-methylene-9-oxo-1,2,3,9-tetrahydropyrrolo<2,1-b>quinazoline 
• 1219010-39-5 C₁₂H₆⁽²⁾H₄N₂O 
• 1219010-38-4 C₁₂H₆⁽²⁾H₄N₂O 

Relevant articles and documents

Radical migration of substituents of aryl groups on quinazolinones derived from N-Acyl cyanamides

A newly designed radical cascade involving N-acyl cyanamides is reported. It builds on aromatic homolytic substitutions as intermediate events and leads to complex heteroaromatic structures via an unprecedented radical migration of a substituent on aryl groups of quinazolinones (hydrogen or alkyl). Mechanistic considerations are detailed, which allowed us to devise fine control over the domino processes. The latter could be predictably stopped at several stages, depending on the reaction conditions. Finally, a surgical introduction of a trifluoromethyl substituent on a quinazolinone was achieved via the reported migration.