121902-52-1Relevant academic research and scientific papers
Formation of 7,7'-Bi-indolyls by Oxidative Dimerization of 4,6-Dimethoxy-2,3-diphenylindole
Black, D. St C.,Choy, Anna,Craig, Donald C.,Ivory, Andrew J.,Kumar, Naresh
, p. 111 - 112 (1989)
4,6-Dimethoxy-2,3-diphenylindole undergoes quinone oxidation to give the corresponding 7,7'-bi-indolyl derivative in high yield.
Reaction of some 4,6-dimethoxyindoles with nitric acid: Nitration and oxidative dimerisation
Keawin, Tinnagon,Rajviroongit, Shuleewan,Black, David Stc.
, p. 853 - 861 (2007/10/03)
A range of 3-substituted-4,6-dimethoxyindoles bearing electron-withdrawing groups in either the 2- or 7-position, can be nitrated using nitric acid in acetonitrile, to give 7-nitro and 2-nitro-indoles, respectively. Those without electron-withdrawing groups undergo oxidative dimerisation at C7, if 2,3-disubstituted, and at C2, if N-methylated and unsubstituted at C2. Some 3-substituted-4,6-dimethoxyindoles can be nitrated using nitric acid in acetonitrile, to give 7-nitro and 2-nitro-indoles. Some undergo oxidative dimerisation at C7, if 2,3-disubstituted, and at C2, if N-methylated and unsubstituted at C2.
Substitution, Oxidation and Addition Reactions at C-7 of Activated Indoles
Black, David St.C.,Bowyer, Michael C.,Catalano, Maria M.,Ivory, Andrew J.,Keller, Paul A.,et al.
, p. 10497 - 10508 (2007/10/02)
4,6-Dimethoxy-2,3-diphenylindole (1) undergoes acylation, bromination, oxidative coupling and acidcatalysed addition to aldehydes at C-7 to produce a range of 7-substituted indoles (3-11), the indolo-isatin (6), the 7,7'-bi-indolyls (14), (16), (18), and
Palladium-catalysed intramolecular cyclisation of 7-halo-N-allyl-indoles
Black,Keller,Kumar
, p. 7601 - 7608 (2007/10/02)
The N-allyl substituted-7-bromo-indoles (4-9) and the N-propargyl-7-bromo-indole(10) were prepared from the 7-bromo-indole (3). Compounds (4) and (7) undergo palladium-catalysed cyclisation to the pyrroloquinolines (11) and (13). Similar reactions of comp
