1219026-95-5

Basic information

• Product Name: (3R)-3-ISOPROPYL-3,4-DIHYDROQUINOXALIN-2(1H)-ONE
• Synonyms: AKOS BBS-00006914;(3R)-3-ISOPROPYL-3,4-DIHYDROQUINOXALIN-2(1H)-ONE
• CAS NO: 1219026-95-5
• Molecular Formula: C11H14N2O
• Molecular Weight: 190.24
• Mol File: 1219026-95-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3R)-3-ISOPROPYL-3,4-DIHYDROQUINOXALIN-2(1H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)-3-ISOPROPYL-3,4-DIHYDROQUINOXALIN-2(1H)-ONE(1219026-95-5)
• EPA Substance Registry System: (3R)-3-ISOPROPYL-3,4-DIHYDROQUINOXALIN-2(1H)-ONE(1219026-95-5)

Safety Data

• Hazardous Substances Data: 1219026-95-5(Hazardous Substances Data)

Usage

General Description

(3R)-3-Isopropyl-3,4-dihydroquinoxalin-2(1H)-one is a chemical compound with a unique structure that contains a quinoxaline ring fused with a cyclic ketone group. It is a chiral compound with the (3R) configuration, indicating that it has a specific three-dimensional arrangement of atoms. This chemical has potential applications in pharmaceutical and medicinal chemistry due to its structural features and potential biological activities. The specific properties and potential uses of (3R)-3-isopropyl-3,4-dihydroquinoxalin-2(1H)-one may be the subject of ongoing research and development in the field of organic chemistry.

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Relevant articles and documents

Metal-free tandem cyclization/hydrosilylation to construct tetrahydroquinoxalines

A one-pot tandem procedure involving cyclization and sequential hydrosilylation of imines and amides under the catalysis of B(C6F5)3 has been developed for the step-economical construction of 1,2,3,4-tetrahydroquinoxalines directly from readily available 1,2-diaminobenzenes, α-ketoesters and low-cost, safe polymethylhydrosiloxane (PMHS). This metal-free approach provides various products in good to excellent yields, and displays a wide range of substrate scope and a high degree of functional group tolerance even to reduction-sensitive moieties. The choice of hydrosilanes is critical to the catalysis, and PMHS has proved to be optimal. Decreasing the amount of PMHS could enable the reaction to stop at the 3,4-dihydroquinoxalin-2(1H)-one stage. The procedure is convenient and scalable, and neither a dried solvent nor an inert atmosphere is required. Moreover, the enantioselective construction of these products was explored, and promising results were achieved.