1219030-63-3Relevant academic research and scientific papers
Synthesis of novel mannich bases containing pyrazolones and indole systems
Ravindranath,Srikanth,Reddy, M. Dastagiri,Begum, S. D. Ishrath
experimental part, p. 443 - 449 (2010/09/20)
Novel mannich bases 7 a-h were synthesized the condensation reaction between 3-Methyl-5-oxo-4-(4'phenyl hydrazono)-4,5-dihydro-pyrazol-1-yl]-acetic acid hydrazide 4 With Isatin yielded the corresponding [3-Methyl5-oxo-4-(4'- substitutedarylhydrazono)-4,5-dihydro-pyrazol-l-yl]-aceticacid(2-oxo-l, 2-dihydro-indol-3-ylidene)hydrazide 6, this was subjected to mannich reaction with cyclic secondary amines in the presence of formaldehyde in DMF to give corresponding hydrazide 7 in excellent yields. The structures of these newly synthesized compounds were characterized by 1H-NMR, Mass, IR and elemental analysis.
