1219089-31-2 Usage
Uses
(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carboxylic Acid is used as a reactant in the synthesis of small-molecule inhibitors of MDM2-p53 protein-protein interaction.
Check Digit Verification of cas no
The CAS Registry Mumber 1219089-31-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,9,0,8 and 9 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1219089-31:
(9*1)+(8*2)+(7*1)+(6*9)+(5*0)+(4*8)+(3*9)+(2*3)+(1*1)=152
152 % 10 = 2
So 1219089-31-2 is a valid CAS Registry Number.
1219089-31-2Relevant articles and documents
MDM2 DEGRADERS AND USES THEREOF
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, (2021/09/26)
The present invention relates to compounds and methods useful for the modulation of mouse double minute 2 homolog ("MDM2") protein via ubiquitination and/or degradation by compounds according to the present invention.
N-SUBSTITUTED PYRROLIDINES
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Page/Page column 35, (2012/01/15)
Compounds of formula and enantiomers and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceu
