1219130-07-0

Basic information

• Product Name: 6-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)picolinic acid
• Synonyms: 6-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)picolinic acid
• CAS NO: 1219130-07-0
• Molecular Formula: C₁₂H₁₅NO₅
• Molecular Weight: 253
• Mol File: 1219130-07-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 401.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.238±0.06 g/cm3(Predicted)
• PKA: 3.46±0.10(Predicted)
• CAS DataBase Reference: 6-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)picolinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)picolinic acid(1219130-07-0)
• EPA Substance Registry System: 6-((2,2-dimethyl-1,3-dioxolan-4-yl)methoxy)picolinic acid(1219130-07-0)

Safety Data

• Hazardous Substances Data: 1219130-07-0(Hazardous Substances Data)

Upstream product

• 21190-87-4 6-bromo-pyridine-2-carboxylic acid 
• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 

Downstream Products

• 1383609-45-7 6-(2,3-dihydroxypropoxy)-N-(2-methyl-4-oxo-3-(3-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-5-yl)picolinamide 

Relevant articles and documents

SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS

Provided herein are novel substituted bicyclic aza-heterocycle sirtuin- modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin- modulating compound in combination with another therapeutic agent.

QUINAZOLINONE AND RELATED ANALOGS AS SIRTUIN MODULATORS

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.