121925-63-1Relevant academic research and scientific papers
Synthesis of α-substituted cyclobutane β-keto esters
Kortmann,Westermann
, p. 931 - 933 (2007/10/02)
The title compounds, α-substituted-β-keto esters 4, were prepared from suitably substituted cyclopropylideneacetates 2 by epoxidation and Wagner-Meerwein rearrangement. The highly strained oxaspiro[2.2]pentane intermediate 3 was isolated.
HIGHLY REGIOSELECTIVE RING-OPENING OF α-SUBSTITUTED CYCLIC ACID ANHYDRIDES CATALYZED BY LIPASE
Hiratake, Jun,Yamamoto, Kazuyoshi,Yamamoto, Yukio,Oda, Jun'ichi
, p. 1555 - 1556 (2007/10/02)
Lipase Amano P irreversibly catalyzed a ring-opening of α-substituted cyclic acid anhydrides 1 preferentially at the less hindered carbonyl group to give monoesters with high regioselectivity.
