1219495-48-3Relevant academic research and scientific papers
Chemoenzymatic synthesis of 1-deaza-pyridoxal 5′-phosphate
Griswold, Wait R.,Toney, Michael D.
, p. 1352 - 1354 (2010)
The first synthesis of 1-deaza-pyridoxal 5′-phosphate (2-formyl-3-hydroxy-4-methylbenzyl phosphate) is described. The chemoenzymatic approach described here is a reliable route to this important isosteric pyridoxal phosphate analogue. This work enables elucidation of the role of the pyridine nitrogen in pyridoxal 5′-phosphate dependent enzymes.
