1219499-45-2Relevant academic research and scientific papers
Design and synthesis of potential new apoptosis agents: hybrid compounds containing perillyl alcohol and new constrained retinoids
Das, Bhaskar C.,Mahalingam, Sakkarapalayam M.,Panda, Lipsa,Wang, Bo,Campbell, Phillp D.,Evans, Todd
scheme or table, p. 1462 - 1466 (2010/04/29)
Novel retinoids 1-3 containing perillyl alcohol were synthesized through the addition of perillyl alcohol to the activated carboxylic acids (retinoids) promoted by DCC (N,N′-dicyclohexyl carbodiimide). A set of structurally and functionally diverse perillyl alcohol derivatives of retinoids were obtained in good yields (78-82%). Biological evaluation of these novel hybrid compounds (containing retinoids and perillyl alcohol) is currently underway in our laboratory.
