121958-40-5

Basic information

• Product Name: (±)-trans-(3-phenyloxiran-2-yl)methyl 4-methylbenzenesulfonate
• CAS NO: 121958-40-5
• Molecular Weight: 304.367
• Mol File: 121958-40-5.mol

Chemical Properties

• CAS DataBase Reference: (±)-trans-(3-phenyloxiran-2-yl)methyl 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (±)-trans-(3-phenyloxiran-2-yl)methyl 4-methylbenzenesulfonate(121958-40-5)
• EPA Substance Registry System: (±)-trans-(3-phenyloxiran-2-yl)methyl 4-methylbenzenesulfonate(121958-40-5)

Safety Data

• Hazardous Substances Data: 121958-40-5(Hazardous Substances Data)

Upstream product

• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 40641-81-4 trans-2,3-epoxy-3-phenylpropan-1-ol 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Rearrangement Reactions of Epoxides in the Presence of 2-Mercaptopyridine N-Oxide Sodium Salt.

Reaction of glycidyl bromides and tosylates with sodium salt of mercaptopyridine N-oxide led to the formation of episulphides.

Synthesis of Tetrahydroquinoline-Embedded Bridged Benzothiaoxazepine-1,1-dioxides

A diastereoselective synthesis of previously unknown tetrahydroquinoline-containing bridged benzothiaoxazepine-1,1-dioxides is presented. The three-step protocol uses readily available N-aryl-2-fluorobenzenesulfonamides and trans-2,3-epoxy-cinnamyl-alcohol-derived tosylates as the starting materials, involves N-alkylation of sulfonamides, intramolecular epoxide ring-opening, and SNAr reactions as the reaction steps, and requires only one chromatographic purification to access the desired products in good overall yields.