1219592-82-1Relevant articles and documents
An expeditious method for the preparation of 2-hydroxy-1,4-dioxane and Its Use in reductive alkylation of amines
Vinter, Adrijana,Avdagic, Amir,Stimac, Vlado,Palej, Ivana,Cikos, Ana,Sunjic, Vitomir,Alihodzic, Sulejman
experimental part, p. 255 - 258 (2010/03/24)
Selective oxidation of diethylene glycol by a ruthenium(VIII) species, obtained in situ from ruthenium(III) chloride-sodium- periodate in the presence of a catalytic quantity of water, affords a monoaldehyde in the form of the internal acetal 2-hydroxy-1,4-dioxane. This compound was used in reductive alkylations of selected primary and secondary amines, demonstrating its utility in the preparation of target structures with the 2-(2-hydroxyethoxy)ethylamino unit. Georg Thieme Verlag Stuttgart.