1219609-18-3

Basic information

• Product Name: ethyl (2-amino-3-{[(1-phenylethyl)amino]carbonyl}-4H-chromen-4-yl)acetate
• CAS NO: 1219609-18-3
• Molecular Weight: 380.444
• Mol File: 1219609-18-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (2-amino-3-{[(1-phenylethyl)amino]carbonyl}-4H-chromen-4-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2-amino-3-{[(1-phenylethyl)amino]carbonyl}-4H-chromen-4-yl)acetate(1219609-18-3)
• EPA Substance Registry System: ethyl (2-amino-3-{[(1-phenylethyl)amino]carbonyl}-4H-chromen-4-yl)acetate(1219609-18-3)

Safety Data

• Hazardous Substances Data: 1219609-18-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1202405-40-0 (R)-2-cyano-N-(1-phenylethyl)acetamide 
• 91-64-5 coumarin 

Relevant articles and documents

Synthesis of 5-Amino-1,10b-dihydro-2 H-chromeno[3,4-c ]pyridine-2,4(3 H)-diones from coumarins and cyanoacetamides under basic conditions

The reaction of various coumarins with cyanoacetamide derivatives under basic conditions (sodium ethoxide, piperidine or 2,2,6,6-tetramethylpiperidine), proceeds via an interesting process which involves skeletal rearrangement of the coumarin, a Michael addition and two cyclizations to afford 5-amino-1,10b-dihydro-2H-chromeno[3,4-c]pyridine-2,4(3H)-diones. The same reaction in the presence of N,N￠-ethane-1,2-diylbis(2-cyanoacetamide) gives the corresponding mono and bis 5-amino-1,10b-dihydro-2H-chromeno[3,4-c] pyridine-2,4(3H)-diones. Georg Thieme Verlag Stuttgart.