1219622-28-2Relevant academic research and scientific papers
Synthesis of N1-substituted 1,2,3,6-tetrahydropyrimidin-2-ones via an unexpected reaction of thiazolo[3,2-a]-pyrimidine derivatives and nitrile oxide
Li, Xiaofang,Yi, Pinggui,Yu, Xianyong
, p. 97 - 101 (2010)
A new class of N1-substituted 1,2,3,6-tetrahydropyrimidin-2-ones was prepared in moderate yields by the reaction of nitrile oxide with thiazolo[3,2-a]pyrimidine derivatives via a domino 1,3-dipolar cycloaddition/ring-opening/ substitution process. The structures of the products were characterized thoroughly by IR, elemental analysis, MS, NMR together with X-ray crystallographic analysis.
