1219634-75-9Relevant academic research and scientific papers
Iron/copper promoted oxidative homo-coupling reaction of terminal alkynes using air as the oxidant
Meng, Xu,Li, Chuanbin,Han, Baochun,Wang, Tiansheng,Chen, Baohua
, p. 4029 - 4031 (2010)
An inexpensive catalytic system, which used a readily available Fe(acac)3 and trace quantity of Cu(acac)2 as the co-catalyst and air as the oxidant for the homo-coupling of terminal alkynes, has been developed. The catalytic system could also apply to the cross-coupling reaction of two different terminal alkynes.
An efficient approach to homocoupling of terminal alkynes: Solvent-free synthesis of 1,3-diynes using catalytic Cu(II) and base
Wang, Dong,Li, Jihui,Li, Na,Gao, Tingting,Hou, Sihua,Chen, Baohua
supporting information; experimental part, p. 45 - 48 (2010/05/17)
We report an environmentally friendly, efficient method for transforming terminal acetylenes into 1,3-diynes based on catalytic amounts of a Cu(ii) salt and base under solvent-free conditions. The developed process conforms to the principles of 'green' chemistry and addresses the shortage of such methods for the synthesis of 1,3-diynes. The reaction is quite general and results in good yields. Interestingly, the system also allows the synthesis of unsymmetric 1,3-diynes by cross-coupling of two different terminal alkynes. Finally, the catalyst can also be recycled.
