1219710-99-2Relevant articles and documents
Synthesis and microbiological evaluation of honokiol derivatives as new antimicrobial agents
Kim, Young-Soo,Lee, Ji-Young,Park, Junho,Hwang, Wangtaek,Lee, Jongsung,Park, Deokhoon
, p. 61 - 65 (2011/12/02)
Honokiol, a major phenolic constituent of Magnolia sp., has various pharmacological activities. To improve the solubility and antibacterial activity of honokiol against E. coli and P. aeruginosa, new honokiol-derivatives (honokiol-acetate, honokiol-succinic acid, honokiol-glycerol, honokiol-glycine, honokiol-glucose and honokiol-mannose) were synthesized and their solubility and antimicrobial activities were investigated. Among the tested compounds, honokiol-glycine showed improved water solubility and antibacterial activities against E. coli and P. aeruginosa when compared to honokiol.