1219727-01-1

Basic information

• Product Name: C₁₉H₂₀N₄O₂
• CAS NO: 1219727-01-1
• Molecular Weight: 336.393
• Mol File: 1219727-01-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₀N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₀N₄O₂(1219727-01-1)
• EPA Substance Registry System: C₁₉H₂₀N₄O₂(1219727-01-1)

Safety Data

• Hazardous Substances Data: 1219727-01-1(Hazardous Substances Data)

Upstream product

• 936250-20-3 3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1219728-23-0 C₁₅H₁₅BrN₂O₂ 

Relevant articles and documents

Discovery of potent and selective urea-based ROCK inhibitors and their effects on intraocular pressure in rats

A series of urea-based Rho kinase (ROCK) inhibitors were designed and evaluated. The discovered compounds had excellent enzyme and cellular potency, high kinase selectivity, high aqueous solubility, good porcine corneal penetration, and appropriate DMPK profiles for topical applications as antiglaucoma therapeutics.